Chemotherapy is a powerful weapon against cancer, but certain cells resist treatment by entering a dormant stage called senescence. These therapy-induced senescent (TIS) cells may become resistant to therapy and even turn aggressive and spread. Detecting TIS cells early could be pivotal in preventing their growth, but current screening methods fall short in speed and accuracy.
New advanced microscopy techniques developed by a team of researchers at Johns Hopkins University and Politecnico di Milano, Fondazione Istituto Nazionale dei Tumori, and Consiglio Nazionale delle Ricerche in Italy may change that, paving the way for clinicians to identify these cells early and adjust treatment options.
